Discovery- 8 novel mammalian steroids and their precursors
Function - endogenous potassium sparing hormones - regulation of serum and tissue electrolyte levels
Initial application - screening test for pre-eclampsia and/or hypertension, cardiovascular disease, renal disease
Therapeutics- replacement hormone therapy when deficiency diseases are documented by the diagnostic applications
Therapeutics - Receptors, antagonists and blockers when proper targets identified